Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453350 | 0.73 | EGFR (0.51) | KDM4EALDH1A1EGFRSRCGABRA1 | |
| SCHEMBL27508643 | 0.71 | ALOX5 (0.53) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8505546 | 0.70 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL5436810 | 0.68 | ALDH1A1 (0.44) | KDM4EALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL8505571 | 0.65 | PARP1 (0.39) | KDM4EALDH1A1EGFRSRCGABRA1 | |
| SCHEMBL5439441 | 0.63 | KDM4E (0.46) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL8503566 | 0.63 | KIF11 (0.50) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL8504405 | 0.62 | KIF11 (0.48) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL31628357 | 0.62 | KIF11 (0.55) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL8506970 | 0.62 | KIF11 (0.55) | KDM4EALDH1A1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144529-A | Heterocyclic compounds, their preparation and use | NOVO NORDISK AS (DK) | 1997-03-05 | — | — | CN | disclosed |