Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826463 | 0.73 | ALOX5 (0.59) | ALOX5KDM4ETSHRALDH1A1GAA | |
| SCHEMBL5851328 | 0.73 | ALOX5 (0.51) | ALOX5KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL7321932 | 0.72 | ALOX5 (0.57) | ALOX5KDM4ETSHRALDH1A1GAA | |
| SCHEMBL417540 | 0.71 | ALOX5 (0.64) | ALOX5KDM4ETSHRALDH1A1GAA | |
| SCHEMBL27453349 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5476505 | 0.70 | KDM4E (0.45) | ALOX5KDM4ETSHRALDH1A1GAA | |
| SCHEMBL9602544 | 0.70 | ALOX5 (1.00) | ALOX5KDM4EGAAFLT3LMNA | |
| SCHEMBL10759696 | 0.70 | ALOX5 (0.51) | ALOX5KDM4ETSHRALDH1A1GAA | |
| SCHEMBL13753636 | 0.69 | DRD2 (0.62) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL22529424 | 0.69 | ALOX5 (0.60) | ALOX5KDM4EALDH1A1FLT3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144529-A | Heterocyclic compounds, their preparation and use | NOVO NORDISK AS (DK) | 1997-03-05 | — | — | CN | claimed |