Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452421 | 0.97 | MAPT (0.48) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452862 | 0.81 | MAPT (0.47) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452355 | 0.81 | MAPT (0.63) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27453308 | 0.80 | ALDH1A1 (0.52) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27453117 | 0.79 | RAB9A (0.60) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27453397 | 0.78 | ALDH1A1 (0.52) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452420 | 0.78 | HTT (0.55) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452210 | 0.78 | MAPT (0.53) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27451638 | 0.77 | MAPT (0.64) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452724 | 0.76 | MAPT (0.67) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |