Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453308 | 0.97 | ALDH1A1 (0.52) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27451276 | 0.94 | RAB9A (0.54) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27451123 | 0.81 | RAB9A (0.68) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27452496 | 0.80 | ADORA2A (0.65) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27452421 | 0.79 | MAPT (0.48) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL27453512 | 0.78 | MAPT (0.47) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL27453518 | 0.77 | RAB9A (0.43) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27452585 | 0.77 | RAB9A (0.58) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27452420 | 0.76 | HTT (0.55) | ALDH1A1RAB9AKDM4ENPC1HPGD | |
| SCHEMBL27451116 | 0.75 | RAB9A (0.77) | ALDH1A1RAB9AKDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |