Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470884 | 0.80 | HTR6 (0.43) | GRIK1GRIK2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL27508533 | 0.76 | SMPD2 (0.39) | GRIK1GRIK2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL27453092 | 0.74 | KDM4E (0.41) | HDAC8HDAC6ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL27862055 | 0.70 | RXRA (0.46) | GRIK1GRIK2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL27453093 | 0.67 | ALDH1A1 (0.35) | ALDH1A1CYP1A2 | |
| SCHEMBL3317966 | 0.65 | RXRA (0.53) | GRIK1GRIK2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL3317971 | 0.65 | RXRA (0.53) | GRIK1GRIK2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL27930959 | 0.65 | RXRA (0.49) | GRIK1GRIK2HDAC8HDAC6SMPD2 | |
| SCHEMBL10706687 | 0.62 | CHAT (0.62) | HDAC8HDAC6ALDH1A1KDM4ELMNA | |
| SCHEMBL10706700 | 0.62 | CHAT (0.62) | HDAC8HDAC6ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148356-C | Benzosulfone derivatives | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1231287-A | Benzosulfone derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-13 | — | — | CN | disclosed |