Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492911 | 0.81 | HTR6 (0.44) | KDM4EMTNR1AMTNR1BPTGS1PTGS2 | |
| SCHEMBL27456879 | 0.74 | GRIK1 (0.37) | KDM4EMTNR1AMTNR1BPTGS1PTGS2 | |
| SCHEMBL27453093 | 0.67 | ALDH1A1 (0.35) | CYP2A6ALDH1A1CYP1A2KMT2A | |
| SCHEMBL6027912 | 0.64 | KDM4E (0.54) | KDM4EMTNR1AMTNR1BPTGS1PTGS2 | |
| SCHEMBL819646 | 0.64 | KDM4E (0.68) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL36974 | 0.64 | KDM4E (0.68) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL31602276 | 0.63 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL553714 | 0.63 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL553715 | 0.63 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL563352 | 0.63 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148356-C | Benzosulfone derivatives | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1231287-A | Benzosulfone derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-13 | — | — | CN | disclosed |