Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577582 | 0.98 | — | — | |
| Phosphoric Acid SCHEMBL27707448 | 0.86 | FDPS (0.46) | — | |
| SCHEMBL28014489 | 0.83 | PKM (0.46) | — | |
| SCHEMBL4911969 | 0.78 | L3MBTL1 (0.49) | — | |
| SCHEMBL5762233 | 0.76 | CHRM2 (0.44) | — | |
| SCHEMBL27979786 | 0.74 | — | — | |
| SCHEMBL3626364 | 0.74 | — | — | |
| SCHEMBL9370817 | 0.74 | KDM1A (0.40) | — | |
| SCHEMBL12394788 | 0.74 | CTSA (0.35) | — | |
| SCHEMBL11624815 | 0.74 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142778-C | Use of thiazolium compounds for preventing and reversing the formation of advanced glycosylation endproducts | ¶ | 2004-03-24 | — | — | CN | disclosed |
| CN-1185736-A | Use of thiazolium compounds for preventing and preverting the formation of advanced glycosylation endproducts | ALTEON INC (US) | 1998-06-24 | — | — | CN | disclosed |