SCHEMBL2745845

SCHEMBL2745845

CCC(c1cccc(C#Cc2ccccc2)c1C(=O)O)c1cccc(C#Cc2ccccc2)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.43
RAB9A P51151 2/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
MMP14 P50281 1/20 0.43
MMP15 P51511 1/20 0.43
MMP16 P51512 1/20 0.43
MMP26 Q9NRE1 1/20 0.43
FFAR1 O14842 11/20 0.41
PTGES O14684 1/20 0.39
CHRM2 P08172 1/20 0.39
S1PR1 P21453 1/20 0.39
FPR1 P21462 1/20 0.39
FPR3 P25089 1/20 0.39
GPR183 P32249 1/20 0.39
APLNR P35414 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
GPR65 Q8IYL9 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747867 0.77 NPC1 (0.53) NPC1RAB9AFFAR1CHRM2S1PR1
SCHEMBL2745848 0.77 MMP2 (0.43) NPC1RAB9AMMP2MMP9MMP12
SCHEMBL10807357 0.74 CA12 (0.55) NPC1RAB9AFFAR1FFAR4SMN1; SMN2
SCHEMBL38694 0.74 NPC1 (0.59) NPC1RAB9AFFAR1SMN1; SMN2KDM4E
SCHEMBL5047626 0.74 NPC1 (0.42) NPC1RAB9AFFAR1SMN1; SMN2KDM4E
SCHEMBL6004163 0.73 POLB (0.47) KDM4EALDH1A1MEN1CYP3A4MAPT
SCHEMBL2746374 0.73 NPC1 (0.45) NPC1RAB9AFFAR1CHRM2S1PR1
SCHEMBL990486 0.73 POLB (0.46) KDM4EALDH1A1MEN1CYP3A4MAPT
SCHEMBL2747002 0.70 CYSLTR2 (0.39) NPC1MMP2MMP9MMP12MMP14
SCHEMBL8614274 0.69 NPC1 (0.56) NPC1RAB9AFFAR1CHRM2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed