SCHEMBL2745848

SCHEMBL2745848

CCC(c1cccc(C(=O)O)c1C#Cc1ccccc1)c1cccc(C(=O)O)c1C#Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
MMP14 P50281 1/20 0.43
MMP15 P51511 1/20 0.43
MMP16 P51512 1/20 0.43
MMP26 Q9NRE1 1/20 0.43
HNF4A P41235 1/20 0.42
PTGES O14684 3/20 0.41
FFAR1 O14842 5/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PAM P19021 1/20 0.37
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713009 0.81 HNF4A (0.55) HNF4AFFAR1NPC1RAB9AAKR1C2
SCHEMBL2747007 0.80 POLB (0.39) POLBALDH1A1ALOX15PTPRCPTPN9
SCHEMBL133469 0.77 ALDH1A1 (0.52) POLBSMN1; SMN2ALDH1A1ALOX15TDP1
SCHEMBL2745845 0.77 NPC1 (0.43) MMP2MMP9MMP12MMP14MMP15
SCHEMBL5667352 0.76 HNF4A (0.50) HNF4AFFAR1NPC1RAB9AAKR1C2
SCHEMBL5047626 0.74 NPC1 (0.42) FFAR1NPC1RAB9APOLBSMN1; SMN2
SCHEMBL6004163 0.73 POLB (0.47) POLBALDH1A1ALOX15TDP1
SCHEMBL5669586 0.73 HNF4A (0.44) HNF4AFFAR1NPC1RAB9AAKR1C2
SCHEMBL990486 0.73 POLB (0.46) POLBALDH1A1ALOX15TDP1
SCHEMBL5668837 0.71 HNF4A (0.49) HNF4ANPC1RAB9AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed