Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969097 | 0.87 | L3MBTL1 (0.64) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL6185775 | 0.86 | GAA (0.59) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL14349480 | 0.86 | L3MBTL1 (0.59) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL14349527 | 0.83 | L3MBTL1 (0.56) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL27726136 | 0.82 | GAA (0.63) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL16152211 | 0.82 | L3MBTL1 (0.62) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL6264941 | 0.82 | L3MBTL1 (0.62) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL12184203 | 0.81 | L3MBTL1 (0.60) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL1487944 | 0.80 | THRB (0.68) | L3MBTL1THRBATMKMT2AMEN1 | |
| SCHEMBL1487940 | 0.80 | THRB (0.68) | L3MBTL1THRBATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143364-A | 5-HT3 receptor agonist, novel thiazole derivative, and intermediate thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1997-02-19 | — | — | CN | disclosed |