Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774637 | 0.83 | TDP1 (0.49) | ADRB2LMNATDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9099925 | 0.83 | ADRB2 (0.47) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL27551703 | 0.80 | ADRB2 (0.47) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL31303455 | 0.78 | MAPT (0.44) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL9098573 | 0.78 | ADRB2 (0.43) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL11462352 | 0.74 | TSHR (0.51) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL9235863 | 0.73 | CYP19A1 (0.55) | TDP1MEN1KMT2AALDH1A1MAPT | |
| 4-Chloro-2-Nitroaniline SCHEMBL131251 | 0.72 | TDP1 (0.64) | LMNATDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9198122 | 0.71 | LMNA (0.51) | ADRB2LMNATDP1MEN1KMT2A | |
| SCHEMBL30802684 | 0.71 | HTR3E (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1141042-A | Enantiomerically pure (+)-liarozole | JANSSEN PHARMACEUTICA NV (BE) | 1997-01-22 | — | — | CN | disclosed |