Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458742 | 0.78 | ADRB2 (0.44) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL28942793 | 0.72 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30322562 | 0.72 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11462352 | 0.70 | TSHR (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL31480794 | 0.70 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10775464 | 0.69 | TDP1 (0.53) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| 4-Chloro-2-Nitroaniline SCHEMBL131251 | 0.69 | TDP1 (0.64) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL11040254 | 0.69 | LPAR1 (0.46) | MAPTLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL20969964 | 0.69 | MAPT (0.48) | MAPTLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL6495434 | 0.69 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269721-B | Compounds for the treatment of respiratory diseases | TMEM16A有限公司 | 2024-12-20 | — | — | CN | disclosed |