Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 4/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089293 | 0.88 | LMNA (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4PTGIR | |
| SCHEMBL11346154 | 0.84 | HSD17B1 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4GRM5 | |
| SCHEMBL6002508 | 0.84 | PTGIR (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PTGIR | |
| SCHEMBL28336888 | 0.81 | KMT2A (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4GRM5 | |
| SCHEMBL27766401 | 0.81 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL28746573 | 0.77 | LTB4R2 (0.47) | LTB4R2ALDH1A1LMNARIPK1KDM4E | |
| SCHEMBL2089292 | 0.76 | HPGD (0.39) | PTGIRALDH1A1PTGER4PTGER3PTGER2 | |
| SCHEMBL27737848 | 0.74 | GRM5 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4GRM5 | |
| SCHEMBL7858429 | 0.74 | CES2 (0.44) | ALDH1A1LMNAKDM4ENPC1PTBP1 | |
| SCHEMBL29460301 | 0.74 | CES2 (0.44) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1495181-A | Method for preparing cyclic oxazolidone containing sulfur and fluorine | �������Ŷ���Լ��������˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1142158-C | Process for preparing cyclic sulfur and fluorine containing oxazolidinones | �������Ŷ���Լ��������˾ | 2004-03-17 | — | — | CN | disclosed |
| CN-1335842-A | Process for preparing cyclic sulfur and fluorine containing oxazolidinones | UPJOHN CO (US) | 2002-02-13 | — | — | CN | disclosed |