Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 4/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728702 | 0.79 | GPR84 (0.67) | NR4A2NPC1RAB9ATDP1IMPDH2 | |
| Hydrochloric Acid SCHEMBL26136311 | 0.78 | GPR84 (0.65) | NR4A2NPC1RAB9ATDP1IMPDH2 | |
| SCHEMBL10835850 | 0.78 | ALDH1A1 (0.59) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27452734 | 0.77 | NR4A2 (0.41) | NR4A2NPC1RAB9ATDP1GPR84 | |
| SCHEMBL28770407 | 0.77 | NR4A2 (0.61) | NR4A2GPR84TUBB1ALDH1A1 | |
| SCHEMBL27728105 | 0.77 | CYP2A6 (0.57) | NR4A2NPC1RAB9ATDP1IMPDH2 | |
| SCHEMBL27984527 | 0.77 | NR4A2 (0.63) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL2535062 | 0.75 | CYP2A6 (0.61) | NR4A2IMPDH2ALDH1A1TNKS2 | |
| SCHEMBL7846022 | 0.74 | KDM4E (0.55) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL28745891 | 0.73 | GABRA1 (0.48) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144800-A | 3-ketoindole derivates taken as potassium channels regulator | BRISTOL MYERS SQUIBB CO (US) | 1997-03-12 | — | — | CN | disclosed |