SCHEMBL27459666

SCHEMBL27459666

CCCCOC(=O)c1ccc(C(=O)OC)c(N)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
HSD17B10 Q99714 3/20 0.49
TSHR P16473 6/20 0.48
LMNA P02545 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP3A4 P08684 3/20 0.48
CYP2C9 P11712 1/20 0.48
PDE4D Q08499 1/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
POLB P06746 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MAPK1 P28482 3/20 0.43
TP53 P04637 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27487328 0.88 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL13853239 0.86 CYP1A2 (0.54) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL5264558 0.85 CYP1A2 (0.53) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL14956928 0.82 ALDH1A1 (0.47) ALDH1A1HSD17B10TSHRLMNAKDM4E
SCHEMBL27519990 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL13853230 0.78 CYP1A2 (0.59) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL11179013 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL28181998 0.76 MEN1 (0.46) ALDH1A1HSD17B10TSHRLMNACYP1A2
SCHEMBL14967079 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRLMNAL3MBTL1
SCHEMBL1007071 0.75 ALDH1A1 (0.51) ALDH1A1HSD17B10TSHRLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1522698-A Antivirals ά 2004-08-25 CN disclosed
CN-1158261-C Antiviral medicine ά 2004-07-21 CN disclosed
CN-1292781-A Antiviral medicine MEDIVIR AB (SE) 2001-04-25 CN disclosed