Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907009 | 0.89 | KDM4E (0.44) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL14967079 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL13853239 | 0.87 | CYP1A2 (0.54) | ALDH1A1KDM4EHSD17B10MAPTMAPK1 | |
| SCHEMBL27486965 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL5264558 | 0.86 | CYP1A2 (0.53) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL20306004 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL5554420 | 0.83 | MAPK1 (0.46) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL27459666 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL31354558 | 0.81 | LCK (0.46) | ALDH1A1GAAHSD17B10MAPTCFTR | |
| SCHEMBL1266209 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4EGAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023858-B2 | Substituted pyrido[2,3-d]pyrimidines as delta-5-desaturase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-2597095-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20130131050-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
| CN-103119043-A | Fused heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL | 2013-05-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131050-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LTB4R2, LTB4R, LTC4S | ALDH1A1 633/4885KDM4E 3749/4885GAA 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.