Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487328 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL27459666 | 0.76 | ALDH1A1 (0.49) | CA12CA1CA2CA9TSHR | |
| SCHEMBL12697419 | 0.74 | CYP1A2 (0.60) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28182000 | 0.73 | TSHR (0.48) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL3885590 | 0.73 | CYP1A2 (0.68) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL4858554 | 0.72 | KMT2A (0.44) | KMT2ACA1CA2TP53 | |
| SCHEMBL17713234 | 0.71 | TSHR (0.62) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL828395 | 0.71 | TSHR (0.62) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL11575455 | 0.71 | TSHR (0.62) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL829178 | 0.71 | TSHR (0.62) | MEN1KMT2ATSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556367-A | A kind of immunotherapy of tumors prediction biomarker PD L2 target polypeptides and its application | 国家纳米科学中心 | 2018-01-09 | — | — | CN | claimed |
| CN-107459559-A | A kind of immunotherapy of tumors prediction biomarker PD L1 target polypeptides and its application | 国家纳米科学中心 | 2017-12-12 | — | — | CN | claimed |
| CN-107286222-A | The polypeptide of targeting tumor stem cells mark CD133 a kind of and its application | 国家纳米科学中心 | 2017-10-24 | — | — | CN | claimed |
| CN-107556367-A | A kind of immunotherapy of tumors prediction biomarker PD L2 target polypeptides and its application | 国家纳米科学中心 | 2018-01-09 | — | — | CN | disclosed |
| CN-107459559-A | A kind of immunotherapy of tumors prediction biomarker PD L1 target polypeptides and its application | 国家纳米科学中心 | 2017-12-12 | — | — | CN | disclosed |
| CN-107286222-A | The polypeptide of targeting tumor stem cells mark CD133 a kind of and its application | 国家纳米科学中心 | 2017-10-24 | — | — | CN | disclosed |