Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92506 | 0.84 | L3MBTL1 (0.63) | SIGMAR1POLBL3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL7563815 | 0.84 | SIGMAR1 (0.50) | SIGMAR1POLBKMT2AL3MBTL1HSD11B1 | |
| SCHEMBL9090627 | 0.83 | L3MBTL1 (0.61) | SIGMAR1POLBL3MBTL1HSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20337874 | 0.83 | L3MBTL1 (0.61) | SIGMAR1POLBKMT2AL3MBTL1HSD11B1 | |
| Hydrochloric Acid SCHEMBL14110124 | 0.83 | SIGMAR1 (0.49) | SIGMAR1POLBKMT2AL3MBTL1HSD11B1 | |
| Hydrochloric Acid SCHEMBL14110120 | 0.83 | SIGMAR1 (0.49) | SIGMAR1CES2CES1POLBKMT2A | |
| Methyl Alcohol SCHEMBL10623350 | 0.81 | HSD11B1 (0.64) | SIGMAR1KMT2AL3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL8672473 | 0.79 | L3MBTL1 (0.56) | SIGMAR1POLBL3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL27303607 | 0.78 | L3MBTL1 (0.59) | SIGMAR1POLBL3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL8299455 | 0.78 | SIGMAR1 (0.67) | SIGMAR1KMT2AL3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109056-A | Imidazopyridines | MERCK PATENT GMBH (DE) | 1995-09-27 | — | — | CN | disclosed |