Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398568 | 0.85 | CRHBP (0.65) | CRHBPCRHR2GAANPSR1POLB | |
| SCHEMBL2531801 | 0.82 | BRD4 (0.42) | CRHBPCRHR2POLBKMT2AALDH1A1 | |
| SCHEMBL8374423 | 0.78 | ALDH1A1 (0.57) | CRHBPCRHR2GAAHSD17B10TSHR | |
| SCHEMBL9998812 | 0.78 | CRHBP (0.53) | CRHBPCRHR2GAAHSD17B10KMT2A | |
| SCHEMBL7919787 | 0.76 | CRHBP (0.51) | CRHBPCRHR2GAANPSR1POLB | |
| SCHEMBL11438428 | 0.76 | CRHBP (0.51) | CRHBPCRHR2GAATSHRKMT2A | |
| SCHEMBL9687040 | 0.76 | CRHBP (0.56) | CRHBPCRHR2GAATSHRKMT2A | |
| SCHEMBL3655893 | 0.74 | CRHBP (0.54) | CRHBPCRHR2GAAPOLBHSD17B10 | |
| SCHEMBL8377061 | 0.74 | CRHBP (0.50) | CRHBPCRHR2GAAKMT2AMEN1 | |
| SCHEMBL7822792 | 0.74 | GAA (0.40) | CRHBPCRHR2GAANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159299-C | Arylalkylpyridzinones | Ĭ��ר���ɷ�����˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1142493-A | Arylalkylpyridzinones | MERCK PATENT GMBH (DE) | 1997-02-12 | — | — | CN | disclosed |