Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398568 | 0.85 | CRHBP (0.65) | CRHBPCRHR2GAAALDH1A1LMNA | |
| SCHEMBL27641818 | 0.84 | CES2 (0.45) | CRHBPCRHR2CES2CES1GAA | |
| SCHEMBL7982563 | 0.84 | ALDH1A1 (0.51) | CRHBPCRHR2CES2CES1GAA | |
| SCHEMBL7858429 | 0.82 | CES2 (0.44) | CES2CES1PARP1ALDH1A1KDM4E | |
| SCHEMBL17671204 | 0.82 | CES2 (0.44) | CRHBPCRHR2CES2CES1GAA | |
| SCHEMBL7985347 | 0.79 | NPC1 (0.51) | CRHBPCRHR2CES2CES1ALDH1A1 | |
| SCHEMBL29460301 | 0.78 | CES2 (0.44) | CRHBPCRHR2CES2CES1PARP1 | |
| SCHEMBL2089025 | 0.78 | CES2 (0.44) | CRHBPCRHR2CES2CES1PARP1 | |
| SCHEMBL9998812 | 0.78 | CRHBP (0.53) | CRHBPCRHR2GAAPARP1ALDH1A1 | |
| SCHEMBL8374423 | 0.78 | ALDH1A1 (0.57) | CRHBPCRHR2GAAPARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5163970-A | NITRO-P-PHENYLENEDIAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS CONTAINING THESE FOR USE ON KERATIN FIBRES | HANS SCHWARZKOPF GMBH (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5067967-A | Nitro dyes for oxidation color dyes | 501 HANS SCHWARZKOPF GMBH (DE) | 1991-11-26 | — | — | US | disclosed |