Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261082 | 0.83 | SMN1; SMN2 (0.54) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL5696642 | 0.82 | KMT2A (0.59) | GAALMNANPC1MAPTRAB9A | |
| SCHEMBL10824946 | 0.81 | ALDH1A1 (0.56) | GAALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9417962 | 0.81 | NPC1 (0.52) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL19294787 | 0.80 | KMT2A (0.46) | GAALMNAMAPTSMN1; SMN2CA2 | |
| SCHEMBL5049713 | 0.80 | LMNA (0.52) | GAALMNANPC1MAPTRAB9A | |
| SCHEMBL29168890 | 0.79 | CA12 (0.53) | GAALMNANPC1MAPTRAB9A | |
| SCHEMBL29325164 | 0.79 | NPC1 (0.47) | GAALMNANPC1MAPTRAB9A | |
| SCHEMBL28337675 | 0.78 | KMT2A (0.47) | GAALMNANPC1MAPTRAB9A | |
| SCHEMBL18688508 | 0.78 | THRB (0.42) | GAALMNANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |