Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384190 | 0.91 | TAS1R3 (0.43) | MEN1KMT2AMAPTLMNAMTNR1A | |
| SCHEMBL27407410 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4435090 | 0.81 | LPAR1 (0.41) | LMNAPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27460977 | 0.81 | HPGD (0.42) | MEN1KMT2AMAPTMTNR1AMTNR1B | |
| SCHEMBL6474679 | 0.80 | L3MBTL1 (0.42) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL27403677 | 0.79 | FABP4 (0.43) | MEN1KMT2AMAPTLMNAMTNR1A | |
| SCHEMBL27385195 | 0.79 | MAPT (0.41) | MEN1KMT2AMAPTLMNAMTNR1A | |
| SCHEMBL27401982 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2AMAPTLMNAMTNR1A | |
| SCHEMBL27420112 | 0.78 | TAS1R3 (0.35) | KMT2AMAPTLMNAMTNR1AMTNR1B | |
| SCHEMBL27387187 | 0.78 | TAS1R3 (0.43) | MAPTPOLBALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080258-C | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pesticides | BAYER AG (DE) | 2002-03-06 | — | — | CN | disclosed |