Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137543 | 0.77 | L3MBTL1 (0.56) | CYP3A4HPGDBCL2BCL2L1PKM | |
| SCHEMBL9726820 | 0.77 | MEN1 (0.51) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL5006969 | 0.77 | CYP3A4 (0.62) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL5000599 | 0.76 | ALOX15 (0.50) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL27714358 | 0.76 | CYP2A6 (0.42) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL27736326 | 0.76 | L3MBTL1 (0.54) | CYP3A4HPGDBCL2BCL2L1PKM | |
| SCHEMBL3618843 | 0.76 | MEN1 (0.67) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL10992564 | 0.75 | L3MBTL1 (0.58) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL28614434 | 0.73 | P2RX3 (0.43) | MEN1KMT2ASMN1; SMN2MAPT | |
| Clorophene SCHEMBL78119 | 0.73 | HIF1A (1.00) | MEN1KMT2ACYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074413-C | Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity | OTSUKA PHARMA CO LTD (JP) | 2001-11-07 | — | — | CN | disclosed |