Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HEXA | P06865 | 3/20 | 0.62 |
| ▸ | HEXB | P07686 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12832289 | 0.89 | HEXA (0.63) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL9091826 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL11629372 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL8664264 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL8984898 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL17733959 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7735555 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL17726925 | 0.85 | ALDH1A1 (0.78) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL8664259 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHEXA | |
| SCHEMBL9093307 | 0.84 | SIRT1 (0.60) | KDM4EALDH1A1LMNAHPGDHEXA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094036-A | Novel asymmetrical commutable bis-naphthalimides | KNOLL AG (DE) | 1994-10-26 | — | — | CN | disclosed |