Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HEXB | P07686 | 8/20 | 0.53 |
| ▸ | OGA | O60502 | 5/20 | 0.53 |
| ▸ | HEXA | P06865 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091826 | 0.97 | KDM4E (0.59) | SIRT1KDM4EALDH1A1LMNAHEXB | |
| SCHEMBL8395338 | 0.95 | SIRT1 (0.66) | SIRT1KDM4EALDH1A1LMNAHEXB | |
| SCHEMBL27461130 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1LMNAHEXBHEXA | |
| SCHEMBL12832289 | 0.82 | HEXA (0.63) | KDM4EALDH1A1LMNAHEXBHEXA | |
| SCHEMBL12660542 | 0.82 | SIRT1 (0.66) | SIRT1KDM4EALDH1A1HEXBOGA | |
| SCHEMBL12660533 | 0.81 | KEAP1 (0.58) | SIRT1KDM4EALDH1A1HEXBOGA | |
| SCHEMBL12660341 | 0.80 | SIRT1 (0.48) | SIRT1KDM4EALDH1A1LMNAHEXB | |
| SCHEMBL12660534 | 0.80 | KEAP1 (0.60) | SIRT1KDM4EALDH1A1HEXBOGA | |
| SCHEMBL8395399 | 0.80 | SIRT1 (0.66) | SIRT1ALDH1A1LMNAHEXBOGA | |
| SCHEMBL8626645 | 0.80 | SIRT1 (0.66) | SIRT1KDM4EALDH1A1LMNAHEXB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554622-A | ACTIVATION OF NONSPECIFIC IMMUNE CELLS, KILLING TUMOR CELLS | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |