Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477025 | 0.83 | FFAR1 (0.56) | PPARGPPARAFFAR1 | |
| SCHEMBL8505233 | 0.79 | GRIK1 (0.54) | PPARGPPARACNR2CNR1ADAMTS5 | |
| SCHEMBL7343532 | 0.79 | GRIK1 (0.54) | PPARGPPARACNR2CNR1ADAMTS5 | |
| SCHEMBL27440508 | 0.78 | MMP2 (0.52) | PPARGPPARAMEN1KMT2AADAMTS5 | |
| SCHEMBL3070798 | 0.71 | PPARG (0.50) | SLC6A9SLC6A5PPARGPPARAUTS2R | |
| SCHEMBL30849665 | 0.71 | PPARG (0.50) | SLC6A9SLC6A5PPARGPPARAUTS2R | |
| SCHEMBL11358241 | 0.70 | PLAAT3 (0.50) | PPARGPPARAMEN1KMT2APLAAT3 | |
| SCHEMBL7346260 | 0.69 | MMP2 (0.64) | PPARGPPARAFFAR1MMP2 | |
| SCHEMBL8504182 | 0.69 | MMP2 (0.64) | PPARGPPARAFFAR1MMP2 | |
| SCHEMBL7867016 | 0.69 | MMP2 (0.64) | PPARGPPARAFFAR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140508-C | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloproteinase inhibitors | — | 2004-03-03 | — | — | CN | claimed |
| CN-1241177-A | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloproteinase inhibitors | BAYER AG (US) | 2000-01-12 | — | — | CN | claimed |
| CN-1140508-C | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloproteinase inhibitors | — | 2004-03-03 | — | — | CN | disclosed |
| CN-1241177-A | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloproteinase inhibitors | BAYER AG (US) | 2000-01-12 | — | — | CN | disclosed |