Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923256 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL10728151 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| Synthalin SCHEMBL336302 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL3069140 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL3072659 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL434733 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL11882788 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| SCHEMBL7718396 | 0.76 | ALOX15 (0.41) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL21715464 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL7146690 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ACYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1119191-A | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | FOURNIER IND & SANTE (FR) | 1996-03-27 | — | — | CN | disclosed |