Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.66 |
| ▸ | F3 | P13726 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | NHERF1 | O14745 | 6/20 | 0.60 |
| ▸ | PYGL | P06737 | 5/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933623 | 0.84 | F7 (0.66) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL12101200 | 0.84 | ALOX15 (0.77) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL4802001 | 0.80 | ALOX15 (0.79) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL6405713 | 0.80 | MAPT (0.70) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL13753365 | 0.80 | ALOX15 (0.79) | F7F3NHERF1PYGLHRH4 | |
| SCHEMBL25782820 | 0.80 | F7 (0.60) | F7F3MEN1KMT2ARXFP1 | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL720582 | 0.80 | F7 (1.00) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL2694131 | 0.80 | F7 (0.74) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL31058769 | 0.79 | NHERF1 (0.78) | F7F3MEN1KMT2ARXFP1 | |
| SCHEMBL7881995 | 0.79 | F7 (0.59) | F7F3MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |