Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461815 | 0.83 | KDM4E (0.54) | PARP1KDM4ERAB9ACSNK1A1DYRK1B | |
| SCHEMBL8648025 | 0.79 | PARP1 (0.67) | PARP1CDC7FGFR1 | |
| SCHEMBL3579908 | 0.78 | PARP1 (0.61) | PARP1KDM4ERAB9APLK4MAP4K4 | |
| SCHEMBL17048129 | 0.77 | KDM4E (0.56) | PARP1KDM4ERAB9APLK4CHEK1 | |
| SCHEMBL6802033 | 0.75 | FGFR1 (0.51) | PARP1KDM4ERAB9AFGFR1 | |
| SCHEMBL27725567 | 0.74 | KEAP1 (0.53) | PARP1CDC7KDM4ERAB9A | |
| SCHEMBL6800084 | 0.74 | PARP1 (0.44) | PARP1KDM4ERAB9ACSNK1A1DYRK1B | |
| SCHEMBL6805509 | 0.74 | PARP1 (0.53) | PARP1CDC7KDM4ERAB9ADHODH | |
| SCHEMBL6806431 | 0.73 | PKN1 (0.42) | PARP1KDM4ERAB9ACSNK1A1DYRK1B | |
| SCHEMBL6804985 | 0.73 | PLK4 (0.39) | PARP1KDM4ERAB9ACSNK1A1DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159007-C | Benzimidazole compounds | ť��˹����ѧ����Ͷ������˾ | 2004-07-28 | — | — | CN | claimed |
| CN-1195985-A | Benzimidazole compounds | UNIV NEWCASTLE VENTURES LTD (GB) | 1998-10-14 | — | — | CN | claimed |
| CN-1159007-C | Benzimidazole compounds | ť��˹����ѧ����Ͷ������˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1195985-A | Benzimidazole compounds | UNIV NEWCASTLE VENTURES LTD (GB) | 1998-10-14 | — | — | CN | disclosed |