Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.39 |
| ▸ | CES1 | P23141 | 7/20 | 0.38 |
| ▸ | CES2 | O00748 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25884983 | 0.83 | CTSK (0.34) | MLYCD | |
| SCHEMBL957996 | 0.81 | CHRM2 (0.33) | EPHX2 | |
| SCHEMBL24256429 | 0.78 | ALDH1A1 (0.36) | MLYCDCA1 | |
| SCHEMBL26894825 | 0.76 | MLYCD (0.38) | MLYCD | |
| SCHEMBL5586241 | 0.75 | FAAH (0.45) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6057133 | 0.75 | CA12 (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1758802 | 0.75 | EPHX2 (0.45) | MEN1KMT2AHSD17B10EPHX2CA12 | |
| SCHEMBL498398 | 0.75 | EPHX2 (0.41) | CES1CES2EPHX2MLYCDCA12 | |
| SCHEMBL20780283 | 0.74 | EPHX2 (0.39) | FAAHMEN1KMT2AHSD17B10EPHX2 | |
| SCHEMBL5300087 | 0.74 | EPHX2 (0.41) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406443-C | Process for preparing quinolone antibiotic intermediates | PROCTER & GAMBLE (US) | 2008-07-30 | — | — | CN | claimed |
| CN-1668599-A | Process for preparing quinolone antibiotic intermediates | PROCTER & GAMBLE (US) | 2005-09-14 | — | — | CN | claimed |
| CN-100406443-C | Process for preparing quinolone antibiotic intermediates | PROCTER & GAMBLE (US) | 2008-07-30 | — | — | CN | disclosed |
| CN-1668599-A | Process for preparing quinolone antibiotic intermediates | PROCTER & GAMBLE (US) | 2005-09-14 | — | — | CN | disclosed |
| CN-1158120-A | Process for the preparation of antimicrobial compounds | PROCTER & GAMBLE (US) | 1997-08-27 | — | — | CN | disclosed |