Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417028 | 0.85 | RAB9A (0.49) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL5165440 | 0.80 | TSHR (0.55) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL30516320 | 0.80 | TSHR (0.55) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL3933287 | 0.79 | KMO (0.54) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL34953 | 0.79 | TSHR (0.70) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL23214310 | 0.79 | LOXL2 (0.46) | TSHRLOXL2CYP4F2CYP4A11RAB9A | |
| SCHEMBL10941453 | 0.77 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28556515 | 0.77 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| Lithium SCHEMBL29634258 | 0.77 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL9943503 | 0.77 | TSHR (0.67) | TSHRLOXL2CYP4F2CYP4A11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152918-A | Novel amido quinoxaline diones, their preparation and use | BASF AG (DE) | 1997-06-25 | — | — | CN | disclosed |