Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576768 | 0.85 | ADORA1 (0.44) | ADORA1NPC1POLBNR4A1RAB9A | |
| SCHEMBL8852563 | 0.77 | NPC1 (0.58) | ADORA1NPC1POLBNR4A1RAB9A | |
| SCHEMBL8558082 | 0.74 | ALDH1A1 (0.34) | POLBSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL8581331 | 0.72 | CYP19A1 (0.39) | MAPK1CYP19A1KMT2AMEN1 | |
| SCHEMBL8566193 | 0.72 | SYK (0.34) | KDM4E | |
| SCHEMBL8577610 | 0.71 | PTPN1 (0.34) | — | |
| SCHEMBL10562297 | 0.70 | SRD5A2 (0.57) | ADORA1NR4A1SMN1; SMN2SRD5A2MAPK1 | |
| SCHEMBL8560086 | 0.70 | CYP11B2 (0.37) | — | |
| SCHEMBL8566575 | 0.70 | ALDH1A1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL1921967 | 0.68 | ROCK2 (0.50) | ADORA1NPC1POLBNR4A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8073441-A | — | — | None | — | — | JP | disclosed |
| US-5773388-A | Pyrimidine derivatives, herbicides and plant growth regulators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5716904-A | FOR BROARD LEAF WEEDS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0764641-A1 | NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0713872-A1 | NOVEL PYRIMIDINE DERIVATIVE, HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-29 | — | — | EP | disclosed |
| JP-H0873441-A | NEW 4,5-SUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEM IND LTD | 1996-03-19 | — | — | JP | disclosed |