SCHEMBL27465376

SCHEMBL27465376

NCc1ccc([C@H](CC2CC2)NC(N)=S)cc1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5456210 0.84 ALDH1A1 (0.37)
SCHEMBL5460628 0.80 MEN1 (0.36)
SCHEMBL27523846 0.80 MEN1 (0.36)
SCHEMBL27465380 0.80 ITGB3 (0.30)
SCHEMBL27481805 0.79 OPRM1 (0.36)
SCHEMBL27482886 0.79 MAPK1 (0.33)
SCHEMBL5454428 0.76 SMN1; SMN2 (0.46)
SCHEMBL27549476 0.76 DPP4 (0.33)
SCHEMBL5456131 0.75 HSD17B1 (0.36)
SCHEMBL5451797 0.74 HSD17B1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1167692-C Aminothiazole derivatives and their use as CRF receptor ligands ʥŵ��-�ϳ�ʵ���ҹ�˾ 2004-09-22 CN disclosed
CN-1370154-A Aminothiazole derivatives and their use as CRF receptor ligands SANOFI SYNTHELABO (FR) 2002-09-18 CN disclosed