Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907830 | 0.84 | GPR119 (0.45) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL30694690 | 0.84 | GPR119 (0.45) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL24299447 | 0.84 | CRBN (0.55) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL31047986 | 0.82 | CRBN (0.45) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL20234679 | 0.82 | CRBN (0.45) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL24299444 | 0.78 | CRBN (0.54) | PDK2GPR119MAPTALDH1A1LMNA | |
| SCHEMBL24481058 | 0.78 | CRBN (0.48) | PDK2GPR119DDB1CRBN | |
| SCHEMBL22951135 | 0.77 | CRBN (0.48) | PDK2GPR119DDB1CRBN | |
| SCHEMBL24501045 | 0.76 | IRAK1 (0.53) | GPR119CRBN | |
| SCHEMBL30962354 | 0.76 | IRAK1 (0.47) | PDK2GPR119CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127022-A1 | HETEROCYCLIC COMPOUNDS TARGETING THE NUDT5 PROTEIN | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |