SCHEMBL27466552

SCHEMBL27466552

CCN(CC1CC1c1ccc(C2CCCC(Cl)C2)cc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.38
TAAR1 Q96RJ0 3/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HTR2C P28335 4/20 0.34
GRM2 Q14416 1/20 0.34
ACHE P22303 1/20 0.33
MAOA P21397 1/20 0.33
HTR2B P41595 2/20 0.33
MAOB P27338 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27468418 0.79 SLC6A4 (0.42) SLC6A4SLC6A2SLC6A3MAOA
SCHEMBL27467452 0.77 SLC6A4 (0.39) SLC6A4SLC6A2SLC6A3
SCHEMBL7325407 0.76 SLC6A4 (0.41) SLC6A4TAAR1SLC6A2SLC6A3GRM2
SCHEMBL27468419 0.75 SLC6A4 (0.32) SLC6A4
SCHEMBL9512625 0.72 AKR1C3 (0.48)
SCHEMBL27482621 0.69 DRD2 (0.40)
Propionaldehyde SCHEMBL27482623 0.69 AKR1C3 (0.41)
SCHEMBL5146739 0.67 ALDH1A1 (0.48)
SCHEMBL27862743 0.66 AKR1C3 (0.43)
SCHEMBL27502073 0.65 CNR2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1154483-C Use of amines to produce drugs for preventing tumour cell proliferation ��ŵ��-ʥ�������ɷ����޹�˾ 2004-06-23 CN disclosed
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN disclosed