SCHEMBL27468418

SCHEMBL27468418

CN(Cc1ccccc1)CC1CC1c1ccc(C2CCCC(Cl)C2)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.42
LSS P48449 4/20 0.40
MAOA P21397 2/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
FFAR4 Q5NUL3 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27467452 0.89 SLC6A4 (0.39) SLC6A4SLC6A2SLC6A3FFAR4
SCHEMBL27466552 0.79 SLC6A4 (0.38) SLC6A4MAOASLC6A2SLC6A3
SCHEMBL7319768 0.76 SLC6A4 (0.45) SLC6A4LSSSLC6A2SLC6A3
SCHEMBL9512625 0.72 AKR1C3 (0.48)
SCHEMBL27468419 0.70 SLC6A4 (0.32) SLC6A4
SCHEMBL17350051 0.68 SLC6A4 (0.43) SLC6A4
Hydrochloric Acid SCHEMBL4533102 0.68 ALDH1A1 (0.49) SLC6A4MAOA
SCHEMBL19715652 0.68 ALDH1A1 (0.49) SLC6A4MAOA
Acetonitrile SCHEMBL7968109 0.68 SIGMAR1 (0.47) FFAR4
SCHEMBL7411787 0.67 SLC6A4 (0.47) SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1154483-C Use of amines to produce drugs for preventing tumour cell proliferation ��ŵ��-ʥ�������ɷ����޹�˾ 2004-06-23 CN disclosed
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN disclosed