Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466728 | 0.81 | SLC6A3 (0.33) | SLC6A3EPHX2EPHX1 | |
| SCHEMBL27483477 | 0.79 | KDM4E (0.41) | SLC6A3EPHX2EPHX1 | |
| SCHEMBL2646128 | 0.75 | KCNH2 (0.48) | ABCB11CNR2CNR1KCNH2 | |
| SCHEMBL27483137 | 0.74 | KMT2A (0.38) | SLC6A3KCNH2EPHX1 | |
| SCHEMBL2646652 | 0.74 | KCNH2 (0.47) | ABCB11CNR2CNR1SLC6A3KCNH2 | |
| SCHEMBL2646633 | 0.74 | KCNH2 (0.45) | ABCB11CNR2CNR1ALOX5APFEN1 | |
| SCHEMBL27467638 | 0.73 | SLC6A3 (0.48) | SLC6A3 | |
| SCHEMBL27482765 | 0.72 | MEN1 (0.50) | SLC6A3KCNH2 | |
| SCHEMBL27465658 | 0.71 | SLC6A3 (0.52) | SLC6A3EPHX2 | |
| SCHEMBL2645963 | 0.71 | KCNH2 (0.48) | ABCB11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |