Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466729 | 0.81 | ABCB11 (0.35) | SLC6A3EPHX2EPHX1 | |
| SCHEMBL27483477 | 0.78 | KDM4E (0.41) | SLC6A3KDM4EEPHX2FFAR1EPHX1 | |
| SCHEMBL27467638 | 0.72 | SLC6A3 (0.48) | SLC6A3MEN1MITFKMT2A | |
| SCHEMBL27482765 | 0.72 | MEN1 (0.50) | SLC6A3MEN1KMT2A | |
| SCHEMBL27465658 | 0.71 | SLC6A3 (0.52) | SLC6A3EPHX2 | |
| SCHEMBL27548017 | 0.70 | APP (0.41) | POLQ | |
| SCHEMBL27548024 | 0.70 | APP (0.40) | POLQ | |
| SCHEMBL27483137 | 0.69 | KMT2A (0.38) | SLC6A3EPHX1MEN1MITFKMT2A | |
| SCHEMBL27482391 | 0.69 | SLC6A3 (0.48) | SLC6A3KDM4EEPHX1MEN1KMT2A | |
| SCHEMBL27467640 | 0.68 | PTGS1 (0.35) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151140-C | Glucokinase activators | - | 2004-05-26 | — | — | CN | disclosed |
| CN-1349519-A | Glucokinase activators | HOFFMANN LA ROCHE (CH) | 2002-05-15 | — | — | CN | disclosed |