Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111743 | 0.81 | ACHE (0.40) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL27543516 | 0.81 | ACHE (0.37) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7102277 | 0.81 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27974432 | 0.79 | LMNA (0.36) | ACHELMNAKDM4EALDH1A1GLA | |
| SCHEMBL3931686 | 0.79 | HCAR2 (0.38) | GAAMAPK1HCAR2DAO | |
| SCHEMBL28111742 | 0.79 | ACHE (0.36) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL27925447 | 0.76 | HCAR2 (0.41) | ACHEKMT2AESR1HIF1ASMN1; SMN2 | |
| SCHEMBL5571174 | 0.75 | RAB9A (0.42) | ACHEKMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL29180176 | 0.74 | ELANE (0.35) | KMT2AALDH1A1ELANEHCAR2DAO | |
| SCHEMBL11901291 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216288-A | A kind of preparation method of Tolfenpyrad impurity | 湖南大学 | 2017-09-29 | — | — | CN | disclosed |
| CN-101339370-B | Electrostatic image developing toner, invisible information toner, electrostatic image developer, process cartridge and image formation apparatus | FUJI XEROX CO LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-101339370-A | Electrostatic image developing toner, invisible information toner, electrostatic image developer, process cartridge and image formation apparatus | FUJI XEROX CO LTD (JP) | 2009-01-07 | — | — | CN | disclosed |
| CN-100358888-C | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1136195-C | Process for synthesizing 3-alkyl-5-pyrazole carboxylate | 四川省化学工业研究设计院 | 2004-01-28 | — | — | CN | disclosed |
| CN-1305996-A | Process for synthesizing 3-alkyl-5-pyrazole carboxylate | SICHUAN PROV DESIGN INST OF CH (CN) | 2001-08-01 | — | — | CN | disclosed |
| CN-1259942-A | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-07-12 | — | — | CN | disclosed |