Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517076 | 0.84 | BCAT2 (0.44) | BCAT2ALOX15CA1CA2CA9 | |
| SCHEMBL2746745 | 0.81 | BCAT2 (0.56) | BCAT2ALOX15CA1CA2CA9 | |
| SCHEMBL28176076 | 0.80 | BCAT2 (0.44) | BCAT2ALOX15CA1CA2CA9 | |
| SCHEMBL27484504 | 0.80 | BCAT2 (0.44) | BCAT2ALOX15CA1CA2CA9 | |
| SCHEMBL28752383 | 0.79 | KDM4E (0.43) | ALOX15CA1CA2CA9CA5A | |
| SCHEMBL18301366 | 0.73 | BCAT2 (0.39) | BCAT2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL3917269 | 0.73 | ALDH1A1 (0.42) | ALOX15CA1CA2CA9LMNA | |
| SCHEMBL9359459 | 0.73 | CDK2 (0.47) | BCAT2CA1CA2CA9LMNA | |
| SCHEMBL1110597 | 0.72 | GAA (0.48) | BCAT2CA1CA2CA9CA5A | |
| SCHEMBL2473273 | 0.72 | MMP2 (0.47) | ALOX15LMNAALDH1A1G6PDCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168720-C | Aryl alkanoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1305465-A | Aryl alkanoylpyridazines | MERCK PATENT GMBH (DE) | 2001-07-25 | — | — | CN | disclosed |