Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756221 | 0.87 | SMN1; SMN2 (0.43) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL28954180 | 0.83 | KMT2A (0.48) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL15549354 | 0.81 | ALOX15 (0.45) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL15547816 | 0.81 | PTGS2 (0.49) | ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL15851159 | 0.81 | TDP1 (0.53) | SMN1; SMN2PPARGKDM4E | |
| SCHEMBL1503350 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL30805171 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL28393941 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL15763905 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL27830688 | 0.79 | CYP4F2 (0.42) | ALDH1A1MAPTSMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131390-A | Plaster containing -2- (p-fluorophenethyl) -3-fluoroallylamine for treating Alzheimer's disease | MERRELL DOW PHARMA (US) | 1996-09-18 | — | — | CN | disclosed |