Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 10/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805171 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2FAAHACLY | |
| Hydrochloric Acid SCHEMBL27592317 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2FAAHACLY | |
| SCHEMBL28306027 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2FAAHKDM4E | |
| SCHEMBL8435546 | 0.86 | ALOX15 (0.55) | ALDH1A1MAPTSMN1; SMN2ACLYKDM4E | |
| SCHEMBL31567693 | 0.85 | ACLY (0.42) | ALDH1A1MAPTSMN1; SMN2FAAHACLY | |
| SCHEMBL1261118 | 0.85 | KDM4E (0.51) | ALDH1A1MAPTSMN1; SMN2FAAHKDM4E | |
| SCHEMBL1261700 | 0.85 | ACLY (0.42) | ALDH1A1MAPTSMN1; SMN2FAAHACLY | |
| SCHEMBL15763905 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2FAAHPPARG | |
| SCHEMBL1260106 | 0.84 | KMT2A (0.43) | ALDH1A1MAPTSMN1; SMN2ACLYKDM4E | |
| SCHEMBL27642915 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799424-B1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT BIO PHARMA CO LTD (JP) | 2016-08-17 | — | — | EP | claimed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | claimed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | claimed |
| EP-2799424-A1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT Bio-Pharma Co., Ltd. (JP) | 2014-11-05 | — | — | EP | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-114040798-A | Novel formulations comprising meflufen | 肿瘤多肽有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-112930214-A | Deuterium-containing compounds | 肿瘤多肽有限公司 | 2021-06-08 | — | — | CN | disclosed |
| WO-2020020097-A1 | PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST | BEIGENE, LTD. (KY) | 2020-01-30 | — | — | WO | disclosed |
| CN-108424367-A | A kind of method that propiolic acid and its derivative are prepared under temperate condition | 中国科学院化学研究所 | 2018-08-21 | — | — | CN | disclosed |
| US-9855260-B2 | Quinolinone derivatives | GLAXOSMITHKLINE LLC (US) | 2018-01-02 | — | — | US | disclosed |
| CN-104321324-B | Substituted condensed imidazole class and pyrazole compound and application thereof | 拜耳知识产权有限责任公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-103998412-B | 2 fluorobenzene phenylpropionic acid derivatives | 日本株式会社 LTT 生物医药 | 2017-05-31 | — | — | CN | disclosed |
| US-4033949-A | Analogs of thromboxane B2 and processes for their synthesis | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4028350-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | FPR1, OPRK1, FPR2 | ALDH1A1 57/4885MAPT 2762/4885SMN1; SMN2 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.