Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802020 | 0.69 | SLC6A4 (0.40) | HTR2AHTR2CRXFP1MEN1KMT2A | |
| SCHEMBL1092569 | 0.66 | PRKCI (0.59) | HTR2AHTR2CSLC6A2CDK4CCND1 | |
| SCHEMBL4557834 | 0.64 | BIRC5 (0.62) | HTR2AHTR2CSLC6A2ROCK2PIM1 | |
| SCHEMBL6623547 | 0.62 | SLC6A2 (0.51) | HTR2AHTR2CRXFP1SLC6A2CDK4 | |
| SCHEMBL31202712 | 0.62 | BRPF1 (0.62) | RXFP1 | |
| SCHEMBL11549772 | 0.62 | MAPT (0.65) | HTR2AHTR2CRXFP1MEN1KMT2A | |
| SCHEMBL4554327 | 0.62 | MAPK8 (0.38) | HTR2AHTR2CRXFP1SLC6A2ROCK2 | |
| SCHEMBL12643016 | 0.62 | ALDH1A1 (0.44) | HTR2AHTR2CROCK2PIM1PIM3 | |
| SCHEMBL4295429 | 0.62 | KCNH2 (0.60) | ROCK2PIM1PIM3BIRC5 | |
| SCHEMBL28337477 | 0.62 | RPS6KA5 (0.47) | HTR2AHTR2CSLC6A2ROCK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154105-A | 4-aryl-1-(indanmethyl, dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines, tetrahydropyridines or piperazines | LUNDBECK & CO AS H (DK) | 1997-07-09 | — | — | CN | disclosed |