Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467850 | 0.88 | KDM4E (0.42) | KDM4EL3MBTL1MEN1KMT2ASCN8A | |
| SCHEMBL28709826 | 0.88 | KDM4E (0.41) | KDM4EL3MBTL1MEN1KMT2ASCN8A | |
| SCHEMBL18724089 | 0.82 | KDM4E (0.39) | KDM4EMEN1KMT2ADRD1LMNA | |
| SCHEMBL28001222 | 0.81 | PIN1 (0.50) | KDM4EL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL4799563 | 0.80 | SMN1; SMN2 (0.62) | KDM4EMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27797567 | 0.79 | KEAP1 (0.59) | KDM4EL3MBTL1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL2964219 | 0.78 | SMN1; SMN2 (0.60) | KDM4EMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL9765665 | 0.78 | KDM4E (0.46) | KDM4EL3MBTL1MEN1KMT2ADRD1 | |
| SCHEMBL409030 | 0.78 | KDM4E (0.55) | KDM4EL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL28165762 | 0.76 | KDM4E (0.47) | KDM4EL3MBTL1KMT2ALMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065357-B1 | Improved process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| EP-2065357-B1 | Improved process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8304550-B2 | Process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304550-B2 | Process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304550-B2 | Process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | SALTIGO GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | SALTIGO GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | SALTIGO GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| EP-2065357-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065356-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065357-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065356-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | ARSA, AHR, AOC2 | KDM4E 629/4885L3MBTL1 4811/4885MEN1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.