Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439921 | 0.85 | KMT2A (0.41) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL28165762 | 0.84 | KDM4E (0.47) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL27467850 | 0.80 | KDM4E (0.42) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL28433387 | 0.77 | KDM4E (0.46) | KDM4ECYP2C19ALDH1A1NPC1P2RX7 | |
| SCHEMBL28441538 | 0.76 | KDM4E (0.41) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL28434195 | 0.76 | KDM4E (0.51) | KDM4ENPSR1LMNATDP1 | |
| SCHEMBL28442218 | 0.73 | KDM4E (0.39) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL15986584 | 0.71 | NPC1 (0.44) | KDM4ECYP2C19ALDH1A1NPC1CYP2D6 | |
| SCHEMBL10263003 | 0.71 | CA2 (0.41) | KDM4EALDH1A1NPC1ALOX5APFEN1 | |
| SCHEMBL28076103 | 0.71 | PIN1 (0.56) | KDM4EALDH1A1NPC1PIN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011251-B | Synthesis method and application of 2- (2-chlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |