Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990363 | 0.80 | NPC1 (0.69) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL7608732 | 0.79 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL878311 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL30851501 | 0.76 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL11202950 | 0.76 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL14771799 | 0.75 | NPC1 (0.62) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL27724251 | 0.75 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL19285700 | 0.75 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL2635336 | 0.75 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL6801114 | 0.74 | CTSV (0.51) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151125-C | Compounds and methods for treating cardiovascular, inflammatory and immune disorders | ǧ��ҩƷ��˾ | 2004-05-26 | — | — | CN | disclosed |
| CN-1163610-A | Compounds and methods for treating cardiovascular, inflammatory and immune disorders | CYTOMED INC (US) | 1997-10-29 | — | — | CN | disclosed |