Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694793 | 0.84 | TDP1 (0.45) | LMNAMAPTKDM4ENPC1MEN1 | |
| SCHEMBL2651269 | 0.82 | ALDH1A1 (0.46) | LMNAMAPTAMY1AKDM4ENPC1 | |
| SCHEMBL27987415 | 0.81 | MAPT (0.45) | LMNAMAPTKDM4ENPC1MEN1 | |
| SCHEMBL10966887 | 0.79 | CYP3A4 (0.49) | LMNAMAPTKDM4ENPC1MEN1 | |
| SCHEMBL28146143 | 0.79 | LMNA (0.43) | LMNAMAPTKDM4ENPC1MEN1 | |
| SCHEMBL27557457 | 0.79 | PTGS2 (0.51) | MAPTKMT2APTPRCS100A4RAB9A | |
| SCHEMBL7263542 | 0.78 | MEN1 (0.45) | HSD17B10CCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL15668204 | 0.76 | CCNB2 (0.53) | HSD17B10CCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL8396786 | 0.76 | PTPRC (0.38) | LMNAMAPTKDM4ENPC1MEN1 | |
| SCHEMBL2029417 | 0.76 | FBP1 (0.45) | HSD17B10MAPTKDM4ENPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138458-A | Treatment and prevention of prostatic cancer | LILLY CO ELI (US) | 1996-12-25 | — | — | CN | disclosed |