Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 known ✓ | P35228 | 5/20 | 0.53 |
| ▸ | NOS1 known ✓ | P29475 | 4/20 | 0.53 |
| ▸ | NOS3 known ✓ | P29474 | 3/20 | 0.53 |
| ▸ | BHMT | Q93088 | 10/20 | 0.53 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.53 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL28674376 | 1.00 | BHMT (0.53) | BHMTBHMT2NOS2NOS1NOS3 | |
| Methionine SCHEMBL8355008 | 0.98 | BHMT (0.52) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL11750418 | 0.98 | BHMT (0.52) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL126688 | 0.96 | — | — | |
| Methionine SCHEMBL162030 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL23361954 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL287590 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL8983115 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 | |
| Racemethionine SCHEMBL5617580 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 | |
| Methionine SCHEMBL5584463 | 0.96 | BHMT (0.57) | BHMTBHMT2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116210697-B | Application of trans-cinnamic acid in improving apple tree rot resistance | 西北农林科技大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-116210697-A | Application of trans-cinnamic acid in improving apple tree rot resistance | 西北农林科技大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113143853-A | Preparation method of efficient cotton polyphenol traditional Chinese medicine extract aqueous solution preparation | 赜誉(上海)生物科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-104147574-A | Heat-clearing and exterior-releasing traditional Chinese medicine composition for treating cold and fever and preparation method thereof | LI HAOCHENG | 2014-11-19 | — | — | CN | disclosed |
| CN-1136830-C | Vitamin D solution holder and containers for transfusions | 株式会社大V制药工厂 | 2004-02-04 | — | — | CN | disclosed |