Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405658 | 0.96 | L3MBTL1 (0.43) | L3MBTL1HRH1ALDH1A1CYP1A2TUBB4A | |
| SCHEMBL27452562 | 0.96 | L3MBTL1 (0.39) | L3MBTL1HRH1ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL27412215 | 0.88 | PKM (0.39) | L3MBTL1HRH1ALDH1A1SMN1; SMN2TUBB4A | |
| SCHEMBL27401370 | 0.88 | L3MBTL1 (0.37) | L3MBTL1HRH1ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL27378919 | 0.86 | CYP1A1 (0.38) | HRH1CYP1A2TUBB4ATUBBTUBA3C | |
| SCHEMBL27366260 | 0.86 | L3MBTL1 (0.45) | L3MBTL1HRH1ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL8458543 | 0.85 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL27446552 | 0.84 | GAA (0.33) | ALDH1A1KMT2A | |
| SCHEMBL27382451 | 0.83 | L3MBTL1 (0.47) | L3MBTL1HRH1ALDH1A1CYP1A2TUBB4A | |
| SCHEMBL27404101 | 0.83 | MEN1 (0.35) | L3MBTL1ALDH1A1CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080262-C | Novel substituted 4-(1H-benzimidazol-2-YL) [1,4] diazepanes useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 2002-03-06 | — | — | CN | disclosed |
| CN-1207097-A | Novel substituted 4- (1H-benzimidazol-2-yl) [1,4] diazepanes useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1999-02-03 | — | — | CN | disclosed |
| CN-1202894-A | Substituted 4-(1H-benzimidzol-2-yl-amino) piepridines useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1998-12-23 | — | — | CN | disclosed |