Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405658 | 0.87 | L3MBTL1 (0.43) | LMNAKMT2AALDH1A1 | |
| SCHEMBL27452562 | 0.86 | L3MBTL1 (0.39) | HCRTR2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL27469100 | 0.84 | L3MBTL1 (0.41) | KMT2AALDH1A1 | |
| SCHEMBL27404101 | 0.84 | MEN1 (0.35) | GAAHCRTR2HTR1AADRA1DADRA1A | |
| SCHEMBL27400179 | 0.84 | BACE1 (0.32) | — | |
| SCHEMBL27402281 | 0.83 | BACE1 (0.48) | GAAALDH1A1 | |
| SCHEMBL8458543 | 0.82 | ALDH1A1 (0.40) | HCRTR2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL27489562 | 0.81 | LMNA (0.36) | GAAHCRTR2LMNAKMT2AALDH1A1 | |
| SCHEMBL27412215 | 0.78 | PKM (0.39) | LMNAKMT2AALDH1A1 | |
| SCHEMBL27401370 | 0.78 | L3MBTL1 (0.37) | LMNAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098264-C | Substituted 4- (1H-benzimidazol-2-yl-amino) piperidines for the treatment of allergic diseases | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1202894-A | Substituted 4-(1H-benzimidzol-2-yl-amino) piepridines useful for the treatment of allergic diseases | HOECHST MARION ROUSSEL INC (US) | 1998-12-23 | — | — | CN | disclosed |